SECURINEGA SUFFRUTICOSA

Other Names:

Flueggea suffruticosa, Hitotsuba-hagi, Pharnaceum suffruticosum, Securinega, Securinega ramiflora, Securinega suffruticosa.

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SECURINEGA SUFFRUTICOSA Overview Information

Securinega suffruticosa is an herb that is used in traditional Chinese medicine (TCM). Its red-brown fruits and leaves are considered edible.

Securinega suffruticosa contains a chemical that can act like a stimulant in the body.

People use Securinega suffruticosa for heartburn, bruising, back pain, multiple sclerosis (MS), and many other conditions, but there is no good scientific evidence to support these uses.

SECURINEGA SUFFRUTICOSA Uses & Effectiveness

We currently have no information for SECURINEGA SUFFRUTICOSA Uses & Effectiveness

SECURINEGA SUFFRUTICOSA Side Effects & Safety

When taken by mouth: There isn't enough reliable information to know if Securinega suffruticosa is safe or what the side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn’t enough reliable information to know if Securinega suffruticosa is safe to use while pregnant or breast-feeding. Stay on the safe side and avoid use.

SECURINEGA SUFFRUTICOSA Interactions

Moderate Interaction Be cautious with this combination

Stimulant drugs interacts with SECURINEGA SUFFRUTICOSA
Stimulants, such as amphetamines and cocaine, speed up the nervous system. By speeding up the nervous system, stimulant medications can increase blood pressure and speed up the heartbeat. Securinega suffruticosa can also speed up the nervous system. Taking Securinega suffruticosa along with stimulant drugs might cause serious problems including increased heart rate and high blood pressure.

SECURINEGA SUFFRUTICOSA Dosing

There isn’t enough reliable information to know what an appropriate dose of Securinega suffruticosa might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

View clinical references for this vitamin or supplement Sources

References:

Han BH, Song CH, Yoon JJ, et al. Anti-Vascular Inflammatory Effect of Ethanol Extract from Securinega suffruticosa in Human Umbilical Vein Endothelial Cells. Nutrients 2020;12(11):3448. View abstract.

Holmes M, Crater AK, Dhudshia B, Thadani AN, Ananvoranich S. Toxoplasma gondii: inhibitory activity and encystation effect of securinine and pyrrolidine derivatives on Toxoplasma growth. Exp Parasitol. 2011;127(2):370-5. View abstract.

Li M, Han S, Zhang G, Wang Y, Ji Z. Antiproliferative activity and apoptosis-inducing mechanism of L-securinine on human breast cancer MCF-7 cells. Pharmazie. 2014;69(3):217-23. View abstract.

Lin TJ, Su CC, Lan CK, et al. Acute poisonings with Breynia officinalis--an outbreak of hepatotoxicity. J Toxicol Clin Toxicol. 2003;41(5):591-4. View abstract.

Raj D, Luczkiewicz M. Securinega suffruticosa. Fitoterapia. 2008;79(6):419-27. View abstract.

Securinega suffruticosa - (Pall.)Rehder. Plants for a Future. [Accessed January 3, 2016]. Available at: https://www.pfaf.org/User/Plant.aspx?LatinName=Securinega+suffruticosa

Yang EJ, Yim EY, Song G, Kim GO, Hyun CG. Inhibition of nitric oxide production in lipopolysaccharide-activated RAW 264.7 macrophages by Jeju plant extracts. Interdiscip Toxicol. 2009;2(4):245-9. View abstract.

Zhang G, Li M, Han S, et al. Induction of human chronic myeloid leukemia K562 cell apoptosis by virosecurinine and its molecular mechanism. Mol Med Rep. 2014;10(5):2365-71. View abstract.

Zhang J, Yao J, Peng S, Li X, Fang J. Securinine disturbs redox homeostasis and elicits oxidative stress-mediated apoptosis via targeting thioredoxin reductase. Biochim Biophys Acta. 2017;1863(1):129-138. View abstract.

Zhou L, Zhao BX, Jiang RW, et al. Securinega alkaloids from the fruits of Flueggea suffruticosa. J Asian Nat Prod Res. 2014;16(6):593-601. View abstract.

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Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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