METHYLSYNEPHRINE Overview Information
Methylsynephrine is a chemical that is made in the lab. It is found in some dietary supplements. According to the US Food and Drug Administration (FDA), methylsynephrine does not meet the definition of a dietary supplement. Also, it is banned by the World Anti-Doping Agency (WADA) for use during competitive sports, and by the Department of Defense (DOD) for use by military personnel.
Methylsynephrine is commonly used for weight loss, athletic performance, lung problems, and other uses, but there is no good scientific evidence to support these uses.
How does it work?
Methylsynephrine is a chemical that stimulates the heart. It might increase blood pressure and heart rate. It might also increase how much blood is pumped around the body.
METHYLSYNEPHRINE Uses & Effectiveness 
Insufficient Evidence for:
- A stronger heart during surgery.
- Asthma.
- Athletic performance.
- Cough.
- Increased energy.
- Low blood pressure.
- Muscle mass.
- Weight loss.
- Other uses.
METHYLSYNEPHRINE Side Effects & Safety
When taken by mouth: Methylsynephrine is POSSIBLY UNSAFE. Because it stimulates the heart, it might cause side effects such as high blood pressure and increased heart rate. Some people also get nausea and vomiting. Do not take products with methylsynephrine on the label.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if methylsynephrine is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Heart disease: Methylsynephrine might increase blood pressure and heart rate. In theory, taking methylsynephrine might make heart disease worse.
High blood pressure: Methylsynephrine might increase blood pressure. In theory, taking methylsynephrine might make high blood pressure worse.
Surgery: Methylsynephrine might increase blood pressure and heart rate. In theory, taking methylsynephrine might interfere with surgery by increasing blood pressure and heart rate. Stop taking methylsynephrine at least 2 weeks before surgery.
Irregular heartbeat (heart arrhythmia): Methylsynephrine might increase heart rate. In theory, taking methylsynephrine might make an irregular heartbeat worse.
METHYLSYNEPHRINE Interactions
Moderate Interaction Be cautious with this combination
- Medications for asthma (Beta-adrenergic agonists) interacts with METHYLSYNEPHRINE
Methylsynephrine might stimulate the heart. Some medications for asthma can also stimulate the heart. Taking methylsynephrine with some medications for asthma might cause too much stimulation and cause heart problems.
Some medications for asthma include albuterol (Proventil, Ventolin, Volmax), metaproterenol (Alupent), terbutaline (Bricanyl, Brethine), and isoproterenol (Isuprel). - Stimulant drugs interacts with METHYLSYNEPHRINE
Stimulant drugs speed up the nervous system and can cause a jittery feeling and a rapid heartbeat. Methylsynephrine might also speed up the heart. Taking methylsynephrine along with stimulant drugs might cause serious problems including increased heart rate and high blood pressure.
Some stimulant drugs include diethylpropion (Tenuate), epinephrine, phentermine (Ionamin), pseudoephedrine (Sudafed), and many others.
METHYLSYNEPHRINE Dosing
The appropriate dose of methylsynephrine depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for methylsynephrine. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
