Reviewer: 1HealthyBee, 55-64 on Treatment for less than 1 month (Consumer)

Comment:
I've been using 800 to 1200 mg of Naturmade 400mg 2-3x a day, for about two weeks. I feel fantastic the fog, pain and depression are gone! It worked so quickly! Also have degenerative disc and have pain daily, taking the SAM-e that pain is 90 percent gone. Also have had joint pain in both shoulders, that too is gone, it's a miracle! Fortunately I have not experienced any side effects, ... Show Full Comment

Comment:
I've been using 800 to 1200 mg of Naturmade 400mg 2-3x a day, for about two weeks. I feel fantastic the fog, pain and depression are gone! It worked so quickly! Also have degenerative disc and have pain daily, taking the SAM-e that pain is 90 percent gone. Also have had joint pain in both shoulders, that too is gone, it's a miracle! Fortunately I have not experienced any side effects, the only exception is slight constipation, which magnesium citrate will easily take care of :)
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Reviewer: MOG, 55-64 Female on Treatment for less than 1 month (Consumer)

Comment:
I started on 2oomg. it caused mild indigestion and lifted my mood within 4 days. Reduced my irritability and relieved night time aches and pains. I increased the dose to 400mg, 200mg twice a day and the idigestion became intolerable. I have reduced to 200mg again and take it with food.

Comment:
I started on 2oomg. it caused mild indigestion and lifted my mood within 4 days. Reduced my irritability and relieved night time aches and pains. I increased the dose to 400mg, 200mg twice a day and the idigestion became intolerable. I have reduced to 200mg again and take it with food.
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Reviewer: beth6.0, 55-64 Female on Treatment for less than 1 month (Consumer)

Comment:
i have been having very bad blowback and leg nerve pain and cramps. this is the only thing I've changed in my supplements. I'm taking 200mg once a day with a vegan multi vitamin and dissolving B12. any one else ever get this ?

Comment:
i have been having very bad blowback and leg nerve pain and cramps. this is the only thing I've changed in my supplements. I'm taking 200mg once a day with a vegan multi vitamin and dissolving B12. any one else ever get this ?
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Reviewer: ddenise, 65-74 Male on Treatment for 1 to 6 months (Consumer)

Comment:
It bothered my stomach

Comment:
It bothered my stomach
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Reviewer: Firefly, 55-64 Female on Treatment for 10 years or more (Consumer)

Comment:
SAMe works better for me than ANY other antidepressant, BUT you have to first learn HOW to TAKE it. I have used it almost every day for over ten years now. I can't recommend ANYTHING more highly for depression. Trial & error has taught me: 1) SAMe MUST be taken on an empty stomach. 2) ONLY use it in blister packs. (If you buy it in a bottle, it is cheaper, but once the air gets to it, it ... Show Full Comment

Comment:
SAMe works better for me than ANY other antidepressant, BUT you have to first learn HOW to TAKE it. I have used it almost every day for over ten years now. I can't recommend ANYTHING more highly for depression. Trial & error has taught me: 1) SAMe MUST be taken on an empty stomach. 2) ONLY use it in blister packs. (If you buy it in a bottle, it is cheaper, but once the air gets to it, it becomes less and less effective, so by the end, you might just be swallowing an empty pill. Don't chance it.) 3) Shop around to see which brand works best for you. 4) Don't give up. 5) If you DO give up and quit taking it, step down GRADUALLY or you could become suicidal. This is true of any antidepressant. 6) Do not use if you are bipolar. SAMe helped me in so many ways, I can't laud it enough. My RA is gone, as is fibromyalgia, CFIDS, anxiety, and it's also great for jet lag, for some crazy reason I don't understand. I have taken it for ten years, and I know it works, because if I ever run out or forget to take it, I get very depressed again. Good news is, an hour after I take it again, I'm my own real, non-foggy, happy self again! I have also heard it is very helpful for liver function, even among alcoholics, but if YOU are alcoholic, please get help to stop that, too. My dad was an alcoholic. You don't want to do that to your kids or family or friends. Or YOURSELF. You're more valuable than alcohol. ;)
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